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Gastrointestinal transcription factors drive lineage-specific developmental programs in organ specification and cancer

Transcription factors (TFs) are spatially and temporally regulated during gut organ specification. Although accumulating evidence shows aberrant reactivation of developmental programs in cancer, little is known about how TFs drive lineage specification in development and cancer. We first defined gas...

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Detalles Bibliográficos
Autores principales: Francis, Roshane, Guo, Haiyang, Streutker, Catherine, Ahmed, Musaddeque, Yung, Theodora, Dirks, Peter B., He, Housheng Hansen, Kim, Tae-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6905862/
https://www.ncbi.nlm.nih.gov/pubmed/31844668
http://dx.doi.org/10.1126/sciadv.aax8898