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LncRNA PTPRE-AS1 modulates M2 macrophage activation and inflammatory diseases by epigenetic promotion of PTPRE

Long noncoding RNAs (lncRNAs) are important regulators of diverse biological processes; however, their function in macrophage activation is undefined. We describe a new regulatory mechanism, where an unreported lncRNA, PTPRE-AS1, targets receptor-type tyrosine protein phosphatase ε (PTPRE) to regula...

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Detalles Bibliográficos
Autores principales: Han, Xiao, Huang, Saihua, Xue, Ping, Fu, Jinrong, Liu, Lijuan, Zhang, Caiyan, Yang, Lan, Xia, Li, Sun, Licheng, Huang, Shau-Ku, Zhou, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6905863/
https://www.ncbi.nlm.nih.gov/pubmed/31844669
http://dx.doi.org/10.1126/sciadv.aax9230