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Dorsal-ventral patterned neural cyst from human pluripotent stem cells in a neurogenic niche

Despite its importance in central nervous system development, development of the human neural tube (NT) remains poorly understood, given the challenges of studying human embryos, and the developmental divergence between humans and animal models. We report a human NT development model, in which NT-li...

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Detalles Bibliográficos
Autores principales: Zheng, Y., Xue, X., Resto-Irizarry, A. M., Li, Z., Shao, Y., Zhao, G., Fu, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6905871/
https://www.ncbi.nlm.nih.gov/pubmed/31844664
http://dx.doi.org/10.1126/sciadv.aax5933