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Characterizing smoking-induced transcriptional heterogeneity in the human bronchial epithelium at single-cell resolution

The human bronchial epithelium is composed of multiple distinct cell types that cooperate to defend against environmental insults. While studies have shown that smoking alters bronchial epithelial function and morphology, its precise effects on specific cell types and overall tissue composition are...

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Detalles Bibliográficos
Autores principales: Duclos, Grant E., Teixeira, Vitor H., Autissier, Patrick, Gesthalter, Yaron B., Reinders-Luinge, Marjan A., Terrano, Robert, Dumas, Yves M., Liu, Gang, Mazzilli, Sarah A., Brandsma, Corry-Anke, van den Berge, Maarten, Janes, Sam M., Timens, Wim, Lenburg, Marc E., Spira, Avrum, Campbell, Joshua D., Beane, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6905872/
https://www.ncbi.nlm.nih.gov/pubmed/31844660
http://dx.doi.org/10.1126/sciadv.aaw3413