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Individual brain organoids reproducibly form cell diversity of the human cerebral cortex

Experimental models of the human brain are needed for basic understanding of its development and disease(1). Human brain organoids hold unprecedented promise for this purpose; however, they are plagued by high organoid-to-organoid variability(2,3). This has raised doubts as to whether developmental...

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Detalles Bibliográficos
Autores principales: Velasco, Silvia, Kedaigle, Amanda J., Simmons, Sean K., Nash, Allison, Rocha, Marina, Quadrato, Giorgia, Paulsen, Bruna, Nguyen, Lan, Adiconis, Xian, Regev, Aviv, Levin, Joshua Z., Arlotta, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906116/
https://www.ncbi.nlm.nih.gov/pubmed/31168097
http://dx.doi.org/10.1038/s41586-019-1289-x