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Quantitative Visualization of Hypoxia and Proliferation Gradients Within Histological Tissue Sections

The formation of hypoxic microenvironments within solid tumors is known to contribute to radiation resistance, chemotherapy resistance, immune suppression, increased metastasis, and an overall poor prognosis. It is therefore crucial to understand the spatial and molecular mechanisms that contribute...

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Detalles Bibliográficos
Autores principales: Zaidi, Mark, Fu, Fred, Cojocari, Dan, McKee, Trevor D., Wouters, Bradly G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906162/
https://www.ncbi.nlm.nih.gov/pubmed/31867322
http://dx.doi.org/10.3389/fbioe.2019.00397