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Understanding the genetics of neuropsychiatric disorders: the potential role of genomic regulatory blocks

Recent genome-wide association studies have identified numerous loci associated with neuropsychiatric disorders. The majority of these are in non-coding regions, and are commonly assigned to the nearest gene along the genome. However, this approach neglects the three-dimensional organisation of the...

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Detalles Bibliográficos
Autores principales: Barešić, Anja, Nash, Alexander Jolyon, Dahoun, Tarik, Howes, Oliver, Lenhard, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906185/
https://www.ncbi.nlm.nih.gov/pubmed/31616042
http://dx.doi.org/10.1038/s41380-019-0518-x