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PTEN Inhibition Protects Against Experimental Intracerebral Hemorrhage-Induced Brain Injury Through PTEN/E2F1/β-Catenin Pathway

Intracerebral hemorrhage (ICH) is a subtype of stroke with highest mortality and morbidity. We have previously demonstrated that dipotassium bisperoxo (picolinato) oxovanadate (V), (bpV[pic]) inhibits phosphatase and tensin homolog (PTEN) and activates extracellular signal-regulated kinase (ERK)1/2....

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Detalles Bibliográficos
Autores principales: Zhao, Dan, Qin, Xing-Ping, Chen, Song-Feng, Liao, Xin-Yu, Cheng, Jing, Liu, Rui, Lei, Yang, Zhang, Zhi-Feng, Wan, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906195/
https://www.ncbi.nlm.nih.gov/pubmed/31866820
http://dx.doi.org/10.3389/fnmol.2019.00281