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Complement pathway changes at age 12 are associated with psychotic experiences at age 18 in a longitudinal population-based study: evidence for a role of stress

The complement cascade is a major component of the immune defence against infection, and there is increasing evidence for a role of dysregulated complement in major psychiatric disorders. We undertook a directed proteomic analysis of the complement signalling pathway (n = 29 proteins) using data-ind...

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Detalles Bibliográficos
Autores principales: Föcking, Melanie, Sabherwal, Sophie, Cates, Hannah M., Scaife, Caitriona, Dicker, Patrick, Hryniewiecka, Magdalena, Wynne, Kieran, Rutten, Bart P. F., Lewis, Glyn, Cannon, Mary, Nestler, Eric J., Heurich, Meike, Cagney, Gerard, Zammit, Stanley, Cotter, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906256/
https://www.ncbi.nlm.nih.gov/pubmed/30635638
http://dx.doi.org/10.1038/s41380-018-0306-z