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Polymorphism in the LASP1 gene promoter region alters cognitive functions of patients with schizophrenia

Schizophrenia’s pathogenesis remains elusive. Cognitive dysfunction is the endophenotype and outcome predictor of schizophrenia. The LIM and SH3 domain protein (LASP1) protein, a component of CNS synapses and dendritic spines, has been related to the N-methyl-D-aspartate receptor (NMDAR) dysfunction...

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Detalles Bibliográficos
Autores principales: Lin, Chieh-Hsin, Yang, Sheng, Huang, Yu-Jhen, Lane, Hsien-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906281/
https://www.ncbi.nlm.nih.gov/pubmed/31827227
http://dx.doi.org/10.1038/s41598-019-55414-1