Prevention of quality decline and delivery of siRNA using exogenous TCTP translocation across the zona pellucida in mouse oocytes

The delivery of exogenous molecules into mammalian oocytes or embryos has been a challenge because of the existence of the protective zona pellucida (ZP) surrounding the oocyte membrane. Here we show that exogenous translationally controlled tumor protein (TCTP) is able to translocate into oocytes a...

Descripción completa

Detalles Bibliográficos
Autores principales: Jeon, Hyuk-Joon, Bai, Guang-Yu, Park, Yuram, Kim, Jae-Sung, Oh, Jeong Su
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906282/
https://www.ncbi.nlm.nih.gov/pubmed/31827205
http://dx.doi.org/10.1038/s41598-019-55449-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906282/
https://www.ncbi.nlm.nih.gov/pubmed/31827205
http://dx.doi.org/10.1038/s41598-019-55449-4

Ejemplares similares