G3BP1 inhibits RNA virus replication by positively regulating RIG-I-mediated cellular antiviral response

Retinoic acid-inducible gene I (RIG-I) is a pattern recognition receptor and is involved in the innate immune response against RNA viruses infection. Here, we demonstrate that the Ras-GTPase-activating protein SH3-domain-binding protein 1 (G3BP1) serves as a positive regulator of the RIG-I-mediated...

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Detalles Bibliográficos
Autores principales: Yang, Wenping, Ru, Yi, Ren, Jingjing, Bai, Juncui, Wei, Junshu, Fu, Shaozu, Liu, Xiangtao, Li, Dan, Zheng, Haixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906297/
https://www.ncbi.nlm.nih.gov/pubmed/31827077
http://dx.doi.org/10.1038/s41419-019-2178-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906297/
https://www.ncbi.nlm.nih.gov/pubmed/31827077
http://dx.doi.org/10.1038/s41419-019-2178-9

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