One-step radiosynthesis of the MCTs imaging agent [(18)F]FACH by aliphatic (18)F-labelling of a methylsulfonate precursor containing an unprotected carboxylic acid group

Monocarboxylate transporters 1 and 4 (MCT1 and MCT4) are involved in tumour development and progression. Their level of expression is particularly upregulated in glycolytic cancer cells and accordingly MCTs are considered as promising drug targets for treatment of a variety of human cancers. The non...

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Detalles Bibliográficos
Autores principales: Sadeghzadeh, Masoud, Moldovan, Rareş-Petru, Teodoro, Rodrigo, Brust, Peter, Wenzel, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906299/
https://www.ncbi.nlm.nih.gov/pubmed/31827199
http://dx.doi.org/10.1038/s41598-019-55354-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906299/
https://www.ncbi.nlm.nih.gov/pubmed/31827199
http://dx.doi.org/10.1038/s41598-019-55354-w

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