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Bioinformatic analysis of peripheral blood RNA-sequencing sensitively detects the cause of late graft loss following overt hyperglycemia in pig-to-nonhuman primate islet xenotransplantation

Clinical islet transplantation has recently been a promising treatment option for intractable type 1 diabetes patients. Although early graft loss has been well studied and controlled, the mechanisms of late graft loss largely remains obscure. Since long-term islet graft survival had not been achieve...

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Detalles Bibliográficos
Autores principales: Kim, Hyun-Je, Moon, Ji Hwan, Chung, Hyunwoo, Shin, Jun-Seop, Kim, Bongi, Kim, Jong-Min, Kim, Jung-Sik, Yoon, Il-Hee, Min, Byoung-Hoon, Kang, Seong-Jun, Kim, Yong-Hee, Jo, Kyuri, Choi, Joungmin, Chae, Heejoon, Lee, Won-Woo, Kim, Sun, Park, Chung-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906328/
https://www.ncbi.nlm.nih.gov/pubmed/31827198
http://dx.doi.org/10.1038/s41598-019-55417-y