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Machine-learning based patient classification using Hepatitis B virus full-length genome quasispecies from Asian and European cohorts

Chronic infection with Hepatitis B virus (HBV) is a major risk factor for the development of advanced liver disease including fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). The relative contribution of virological factors to disease progression has not been fully defined and tools aiding t...

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Detalles Bibliográficos
Autores principales: Mueller-Breckenridge, Alan J., Garcia-Alcalde, Fernando, Wildum, Steffen, Smits, Saskia L., de Man, Robert A., van Campenhout, Margo J. H., Brouwer, Willem P., Niu, Jianjun, Young, John A. T., Najera, Isabel, Zhu, Lina, Wu, Daitze, Racek, Tomas, Hundie, Gadissa Bedada, Lin, Yong, Boucher, Charles A., van de Vijver, David, Haagmans, Bart L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906359/
https://www.ncbi.nlm.nih.gov/pubmed/31827222
http://dx.doi.org/10.1038/s41598-019-55445-8