Stochastic multicellular modeling of x-ray irradiation, DNA damage induction, DNA free-end misrejoining and cell death

The repair or misrepair of DNA double-strand breaks (DSBs) largely determines whether a cell will survive radiation insult or die. A new computational model of multicellular, track structure-based and pO(2)-dependent radiation-induced cell death was developed and used to investigate the contribution...

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Detalles Bibliográficos
Autores principales: Forster, Jake C., Douglass, Michael J. J., Phillips, Wendy M., Bezak, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906404/
https://www.ncbi.nlm.nih.gov/pubmed/31827107
http://dx.doi.org/10.1038/s41598-019-54941-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906404/
https://www.ncbi.nlm.nih.gov/pubmed/31827107
http://dx.doi.org/10.1038/s41598-019-54941-1

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