Finnish Parkinson’s disease study integrating protein-protein interaction network data with exome sequencing analysis

Variants associated with Parkinson’s disease (PD) have generally a small effect size and, therefore, large sample sizes or targeted analyses are required to detect significant associations in a whole exome sequencing (WES) study. Here, we used protein-protein interaction (PPI) information on 36 gene...

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Detalles Bibliográficos
Autores principales: Siitonen, Ari, Kytövuori, Laura, Nalls, Mike A., Gibbs, Raphael, Hernandez, Dena G., Ylikotila, Pauli, Peltonen, Markku, Singleton, Andrew B., Majamaa, Kari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906405/
https://www.ncbi.nlm.nih.gov/pubmed/31827228
http://dx.doi.org/10.1038/s41598-019-55479-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906405/
https://www.ncbi.nlm.nih.gov/pubmed/31827228
http://dx.doi.org/10.1038/s41598-019-55479-y

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