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Induction of specific adaptive immune responses by immunization with newly designed artificial glycosphingolipids

We previously found that artificial glycosphingolipids (artGSLs) containing very-long-chain fatty acids behave as strong immunogens in mice and promote the production of antibodies recognizing the oligosaccharide portion of artGSLs as the epitope. Here, we report that the oligosaccharide structure o...

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Detalles Bibliográficos
Autores principales: Okuda, Tetsuya, Shimizu, Kayoko, Hasaba, Satoshi, Date, Mutsuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906409/
https://www.ncbi.nlm.nih.gov/pubmed/31827147
http://dx.doi.org/10.1038/s41598-019-55088-9