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Induction of specific adaptive immune responses by immunization with newly designed artificial glycosphingolipids
We previously found that artificial glycosphingolipids (artGSLs) containing very-long-chain fatty acids behave as strong immunogens in mice and promote the production of antibodies recognizing the oligosaccharide portion of artGSLs as the epitope. Here, we report that the oligosaccharide structure o...
Autores principales: | Okuda, Tetsuya, Shimizu, Kayoko, Hasaba, Satoshi, Date, Mutsuhiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906409/ https://www.ncbi.nlm.nih.gov/pubmed/31827147 http://dx.doi.org/10.1038/s41598-019-55088-9 |
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