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A higher throughput assay for quantification of melphalan-induced DNA damage in peripheral blood mononuclear cells
Inter-individual differences in DNA adduct formation and repair influence the response to melphalan treatment, however, further clinical investigation of this variability requires a logistically feasible and reproducible bioassay. Our improved fluorescence-based QPCR-block assay is robust, has good...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906414/ https://www.ncbi.nlm.nih.gov/pubmed/31827154 http://dx.doi.org/10.1038/s41598-019-55161-3 |