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Extracellular vesicles from symbiotic vaginal lactobacilli inhibit HIV-1 infection of human tissues

The vaginal microbiota, dominated by Lactobacillus spp., plays a key role in preventing HIV-1 transmission. Here, we investigate whether the anti-HIV effect of lactobacilli is mediated by extracellular vesicles (EVs) released by these bacteria. Human cervico-vaginal and tonsillar tissues ex vivo, an...

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Detalles Bibliográficos
Autores principales: Ñahui Palomino, Rogers A., Vanpouille, Christophe, Laghi, Luca, Parolin, Carola, Melikov, Kamran, Backlund, Peter, Vitali, Beatrice, Margolis, Leonid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906448/
https://www.ncbi.nlm.nih.gov/pubmed/31827089
http://dx.doi.org/10.1038/s41467-019-13468-9