Characterization of A Bifunctional Synthetic RNA Aptamer and A Truncated Form for Ability to Inhibit Growth of Non-Small Cell Lung Cancer

An in vitro-transcribed RNA aptamer (trans-RA16) that targets non-small cell lung cancer (NSCLC) was previously identified through in vivo SELEX. Trans-RA16 can specifically target and inhibit human NCI-H460 cells in vitro and xenograft tumors in vivo. Here, in a follow-up study, we obtained a chemi...

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Detalles Bibliográficos
Autores principales: Wang, Hanlu, Qin, Meng, Liu, Rihe, Ding, Xinxin, Chen, Irvin S. Y., Jiang, Yongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906461/
https://www.ncbi.nlm.nih.gov/pubmed/31827170
http://dx.doi.org/10.1038/s41598-019-55280-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906461/
https://www.ncbi.nlm.nih.gov/pubmed/31827170
http://dx.doi.org/10.1038/s41598-019-55280-x

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