Endothelial Progenitor Cells inhibit jaw osteonecrosis in a rat model: A major adverse effect of bisphosphonate therapy

Medication-related osteonecrosis of the jaw (MRONJ) is a serious adverse effect of antiresorptive and antiangiogenic therapies. MRONJ is identified by chronic wounds in the oral mucosa associated with exposed necrotic bone. We hypothesized that zoledronic acid (ZOL) impairs keratinocyte and fibrobla...

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Detalles Bibliográficos
Autores principales: Tamari, Tal, Elimelech, Rina, Cohen, Gal, Cohen, Talia, Doppelt, Ofri, Eskander-Hashoul, Lana, Zigdon-Giladi, Hadar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906486/
https://www.ncbi.nlm.nih.gov/pubmed/31827217
http://dx.doi.org/10.1038/s41598-019-55383-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906486/
https://www.ncbi.nlm.nih.gov/pubmed/31827217
http://dx.doi.org/10.1038/s41598-019-55383-5

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