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Endothelial Progenitor Cells inhibit jaw osteonecrosis in a rat model: A major adverse effect of bisphosphonate therapy
Medication-related osteonecrosis of the jaw (MRONJ) is a serious adverse effect of antiresorptive and antiangiogenic therapies. MRONJ is identified by chronic wounds in the oral mucosa associated with exposed necrotic bone. We hypothesized that zoledronic acid (ZOL) impairs keratinocyte and fibrobla...
Autores principales: | Tamari, Tal, Elimelech, Rina, Cohen, Gal, Cohen, Talia, Doppelt, Ofri, Eskander-Hashoul, Lana, Zigdon-Giladi, Hadar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906486/ https://www.ncbi.nlm.nih.gov/pubmed/31827217 http://dx.doi.org/10.1038/s41598-019-55383-5 |
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