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Cell-based interferon gene therapy using proliferation-controllable, interferon-releasing mesenchymal stem cells

An important safety concern on cell-based gene therapy is that few methods have been available to control the proliferation and functioning of therapeutic protein-expressing cells after transplantation. We previously reported that the proliferation and functioning of the cells transfected with herpe...

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Detalles Bibliográficos
Autores principales: Tsujimura, Mari, Kusamori, Kosuke, Katsumi, Hidemasa, Sakane, Toshiyasu, Yamamoto, Akira, Nishikawa, Makiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906518/
https://www.ncbi.nlm.nih.gov/pubmed/31827180
http://dx.doi.org/10.1038/s41598-019-55269-6