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Cell-based interferon gene therapy using proliferation-controllable, interferon-releasing mesenchymal stem cells
An important safety concern on cell-based gene therapy is that few methods have been available to control the proliferation and functioning of therapeutic protein-expressing cells after transplantation. We previously reported that the proliferation and functioning of the cells transfected with herpe...
Autores principales: | Tsujimura, Mari, Kusamori, Kosuke, Katsumi, Hidemasa, Sakane, Toshiyasu, Yamamoto, Akira, Nishikawa, Makiya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906518/ https://www.ncbi.nlm.nih.gov/pubmed/31827180 http://dx.doi.org/10.1038/s41598-019-55269-6 |
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