Structural studies of the MMP-3 interaction with triple-helical collagen introduce new roles for the enzyme in tissue remodelling

Matrix metalloproteinase-3 (MMP-3) participates in normal extracellular matrix turnover during embryonic development, organ morphogenesis and wound healing, and in tissue-destruction associated with aneurysm, cancer, arthritis and heart failure. Despite its inability to cleave triple-helical collage...

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Detalles Bibliográficos
Autores principales: Manka, Szymon W., Bihan, Dominique, Farndale, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906530/
https://www.ncbi.nlm.nih.gov/pubmed/31827179
http://dx.doi.org/10.1038/s41598-019-55266-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906530/
https://www.ncbi.nlm.nih.gov/pubmed/31827179
http://dx.doi.org/10.1038/s41598-019-55266-9

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