RSAT variation-tools: An accessible and flexible framework to predict the impact of regulatory variants on transcription factor binding

Gene regulatory regions contain short and degenerated DNA binding sites recognized by transcription factors (TFBS). When TFBS harbor SNPs, the DNA binding site may be affected, thereby altering the transcriptional regulation of the target genes. Such regulatory SNPs have been implicated as causal va...

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Detalles Bibliográficos
Autores principales: Santana-Garcia, Walter, Rocha-Acevedo, Maria, Ramirez-Navarro, Lucia, Mbouamboua, Yvon, Thieffry, Denis, Thomas-Chollier, Morgane, Contreras-Moreira, Bruno, van Helden, Jacques, Medina-Rivera, Alejandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906655/
https://www.ncbi.nlm.nih.gov/pubmed/31871587
http://dx.doi.org/10.1016/j.csbj.2019.09.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906655/
https://www.ncbi.nlm.nih.gov/pubmed/31871587
http://dx.doi.org/10.1016/j.csbj.2019.09.009

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