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Rac activation is key to cell motility and directionality: An experimental and modelling investigation

Cell migration is a tightly-regulated process that involves protein gradients formed by the Rho family of GTPases, including Rho and Rac. The front (rear) of cells is generally characterized by higher active Rac (Rho) and lower active Rho (Rac) concentrations. Protein clusters, called adhesions, tha...

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Detalles Bibliográficos
Autores principales: Lyda, Jessica K., Tan, Zhang L., Rajah, Abira, Momi, Asheesh, Mackay, Laurent, Brown, Claire M., Khadra, Anmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906685/
https://www.ncbi.nlm.nih.gov/pubmed/31871589
http://dx.doi.org/10.1016/j.csbj.2019.10.002