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Rac activation is key to cell motility and directionality: An experimental and modelling investigation
Cell migration is a tightly-regulated process that involves protein gradients formed by the Rho family of GTPases, including Rho and Rac. The front (rear) of cells is generally characterized by higher active Rac (Rho) and lower active Rho (Rac) concentrations. Protein clusters, called adhesions, tha...
Autores principales: | Lyda, Jessica K., Tan, Zhang L., Rajah, Abira, Momi, Asheesh, Mackay, Laurent, Brown, Claire M., Khadra, Anmar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906685/ https://www.ncbi.nlm.nih.gov/pubmed/31871589 http://dx.doi.org/10.1016/j.csbj.2019.10.002 |
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