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Glutathione peroxidase-1 regulates adhesion and metastasis of triple-negative breast cancer cells via FAK signaling

Triple-negative breast cancer (TNBC) cells, which do not express genes for estrogen receptor (ER), progesterone receptor (PR), and Her2/neu, develop highly aggressive and metastatic tumors resistant to chemo- and hormonal therapies. We found that expression of glutathione peroxidase-1 (Gpx1) is sile...

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Detalles Bibliográficos
Autores principales: Lee, Eunkyung, Choi, Ahyoung, Jun, Yukyung, Kim, Namhee, Yook, Jong In, Kim, Soo Youl, Lee, Sanghyuk, Kang, Sang Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906704/
https://www.ncbi.nlm.nih.gov/pubmed/31926619
http://dx.doi.org/10.1016/j.redox.2019.101391