Good Manufacturing Practice Strategy for Antibody–Drug Conjugate Synthesis Using Site-Specific Chemical Conjugation: First-Generation AJICAP

[Image: see text] The development of antibody–drug conjugates (ADCs) is in great demand in the oncology field. With the goal of maximizing the therapeutic index, the conjugation technology to produce ADCs has been shifted to a site-specific manner; however, it is still challenging to establish robus...

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Detalles Bibliográficos
Autores principales: Matsuda, Yutaka, Clancy, Colin, Tawfiq, Zhala, Robles, Veronica, Mendelsohn, Brian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906777/
https://www.ncbi.nlm.nih.gov/pubmed/31858041
http://dx.doi.org/10.1021/acsomega.9b02419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906777/
https://www.ncbi.nlm.nih.gov/pubmed/31858041
http://dx.doi.org/10.1021/acsomega.9b02419

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