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Activation of TGR5 Partially Alleviates High Glucose-Induced Cardiomyocyte Injury by Inhibition of Inflammatory Responses and Oxidative Stress

High glucose- (HG-) induced cardiomyocyte injury is the leading cause of diabetic cardiomyopathy, which is associated with the induction of inflammatory responses and oxidative stress. TGR5 plays an important role in the regulation of glucose metabolism. However, whether TGR5 has cardioprotective ef...

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Detalles Bibliográficos
Autores principales: Deng, Li, Chen, Xuxin, Zhong, Yi, Wen, Xing, Cai, Ying, Li, Jiafu, Fan, Zhongcai, Feng, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906824/
https://www.ncbi.nlm.nih.gov/pubmed/31871553
http://dx.doi.org/10.1155/2019/6372786