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ALDH2 Overexpression Alleviates High Glucose-Induced Cardiotoxicity by Inhibiting NLRP3 Inflammasome Activation

Although the underlying mechanisms of diabetes-induced myocardial injury have not been fully illuminated, the inflammation reaction has been reported intently linked with diabetes. The nucleotide binding oligomerization domain-like receptor protein 3 (NLRP3) inflammasome, the key component of pyropt...

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Detalles Bibliográficos
Autores principales: Cao, Ruiping, Fang, Dian, Wang, Jiahui, Yu, Ying, Ye, Hongwei, Kang, Pinfang, Li, Zhenghong, Wang, Hongju, Gao, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906837/
https://www.ncbi.nlm.nih.gov/pubmed/31871948
http://dx.doi.org/10.1155/2019/4857921