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The Ubiquitin-Specific Protease 18 Promotes Hepatitis C Virus Production by Increasing Viral Infectivity

BACKGROUND AND AIMS: Ubiquitin-specific protease 18 (USP18) is involved in immunoregulation and response to interferon- (IFN-) based treatment in patients chronically infected with hepatitis C virus (HCV). We investigated whether and how its upregulation alters HCV infection. METHODS: Overexpression...

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Detalles Bibliográficos
Autores principales: Li, Yujia, Ma, Max Xuezhong, Qin, Bo, Lin, Liang-Tzung, Richardson, Christopher D., Feld, Jordan, McGilvray, Ian D., Chen, Limin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906844/
https://www.ncbi.nlm.nih.gov/pubmed/31871427
http://dx.doi.org/10.1155/2019/3124745