Molecular Mechanism of Matrine from Sophora alopecuroides in the Reversing Effect of Multi-Anticancer Drug Resistance in K562/ADR Cells

Multidrug resistance is the main obstacle to current chemotherapies. In this study, we evaluated the reversing effect of matrine, the principal alkaloid derived from Sophora alopecuroides, on chemoresistant leukemia K562/ADR cells. Matrine in a range of the nontoxic concentration was employed in the...

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Detalles Bibliográficos
Autores principales: Chen, Zhi, Nishimura, Nobuhiro, Okamoto, Takayuki, Wada, Koichiro, Naora, Kohji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906886/
https://www.ncbi.nlm.nih.gov/pubmed/31871929
http://dx.doi.org/10.1155/2019/1269532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906886/
https://www.ncbi.nlm.nih.gov/pubmed/31871929
http://dx.doi.org/10.1155/2019/1269532

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