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Molecular Mechanism of Matrine from Sophora alopecuroides in the Reversing Effect of Multi-Anticancer Drug Resistance in K562/ADR Cells
Multidrug resistance is the main obstacle to current chemotherapies. In this study, we evaluated the reversing effect of matrine, the principal alkaloid derived from Sophora alopecuroides, on chemoresistant leukemia K562/ADR cells. Matrine in a range of the nontoxic concentration was employed in the...
Autores principales: | Chen, Zhi, Nishimura, Nobuhiro, Okamoto, Takayuki, Wada, Koichiro, Naora, Kohji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906886/ https://www.ncbi.nlm.nih.gov/pubmed/31871929 http://dx.doi.org/10.1155/2019/1269532 |
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