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ALCOHOL METABOLISM CONTRIBUTES TO BRAIN HISTONE ACETYLATION

Emerging evidence suggests that epigenetic regulation is dependent on metabolic state, implicating specific metabolic factors in neural functions that drive behavior(1). In neurons, histone acetylation relies on the metabolite acetyl-CoA that is produced from acetate by chromatin-bound acetyl-CoA sy...

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Detalles Bibliográficos
Autores principales: Mews, P, Egervari, G, Nativio, R, Sidoli, S, Donahue, G, Lombroso, SI, Alexander, DC, Riesche, SL, Heller, EA, Nestler, EJ, Garcia, BA, Berger, SL
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907081/
https://www.ncbi.nlm.nih.gov/pubmed/31645761
http://dx.doi.org/10.1038/s41586-019-1700-7