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Distinct DNA methylation targets by aging and chronic inflammation: a pilot study using gastric mucosa infected with Helicobacter pylori

BACKGROUND: Aberrant DNA methylation is induced by aging and chronic inflammation in normal tissues. The induction by inflammation is widely recognized as acceleration of age-related methylation. However, few studies addressed target genomic regions and the responsible factors in a genome-wide manne...

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Detalles Bibliográficos
Autores principales: Yamashita, Satoshi, Nanjo, Sohachi, Rehnberg, Emil, Iida, Naoko, Takeshima, Hideyuki, Ando, Takayuki, Maekita, Takao, Sugiyama, Toshiro, Ushijima, Toshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907118/
https://www.ncbi.nlm.nih.gov/pubmed/31829249
http://dx.doi.org/10.1186/s13148-019-0789-8