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Structures of fibrils formed by α-synuclein hereditary disease mutant H50Q reveal new polymorphs
Deposits of amyloid fibrils of α-synuclein are the histological hallmarks of Parkinson’s disease, dementia with Lewy bodies, and multiple system atrophy, with hereditary mutations in α-synuclein linked to the first two of these conditions. Seeing the changes to the structures of amyloid fibrils bear...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907165/ https://www.ncbi.nlm.nih.gov/pubmed/31695184 http://dx.doi.org/10.1038/s41594-019-0322-y |