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Structures of fibrils formed by α-synuclein hereditary disease mutant H50Q reveal new polymorphs

Deposits of amyloid fibrils of α-synuclein are the histological hallmarks of Parkinson’s disease, dementia with Lewy bodies, and multiple system atrophy, with hereditary mutations in α-synuclein linked to the first two of these conditions. Seeing the changes to the structures of amyloid fibrils bear...

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Detalles Bibliográficos
Autores principales:	Boyer, David R., Li, Binsen, Sun, Chuanqi, Fan, Weijia, Sawaya, Michael R., Jiang, Lin, Eisenberg, David S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907165/ https://www.ncbi.nlm.nih.gov/pubmed/31695184 http://dx.doi.org/10.1038/s41594-019-0322-y

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