Efficacy and safety of dexmedetomidine for prevention of withdrawal syndrome in the pediatric intensive care unit: protocol for an adaptive, multicenter, randomized, double-blind, placebo-controlled, non-profit clinical trial

BACKGROUND: Prolonged treatment with analgesic and sedative drugs in the pediatric intensive care unit (PICU) may lead to undesirable effects such as dependence and tolerance. Moreover, during analgosedation weaning, patients may develop clinical signs of withdrawal, known as withdrawal syndrome (WS...

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Detalles Bibliográficos
Autores principales: Mondardini, Maria Cristina, Sperotto, Francesca, Daverio, Marco, Caramelli, Fabio, Gregori, Dario, Caligiuri, Maria Francesca, Vitale, Francesca, Cecini, Maria Teresa, Piastra, Marco, Mancino, Aldo, Pettenazzo, Andrea, Conti, Giorgio, Amigoni, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907190/
https://www.ncbi.nlm.nih.gov/pubmed/31829274
http://dx.doi.org/10.1186/s13063-019-3793-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907190/
https://www.ncbi.nlm.nih.gov/pubmed/31829274
http://dx.doi.org/10.1186/s13063-019-3793-6

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