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Drug screening approach combines epigenetic sensitization with immunochemotherapy in cancer

BACKGROUND: The epigenome plays a key role in cancer heterogeneity and drug resistance. Hence, a number of epigenetic inhibitors have been developed and tested in cancers. The major focus of most studies so far has been on the cytotoxic effect of these compounds, and only few have investigated the a...

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Detalles Bibliográficos
Autores principales: Facciotto, Chiara, Casado, Julia, Turunen, Laura, Leivonen, Suvi-Katri, Tumiati, Manuela, Rantanen, Ville, Kauppi, Liisa, Lehtonen, Rainer, Leppä, Sirpa, Wennerberg, Krister, Hautaniemi, Sampsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907220/
https://www.ncbi.nlm.nih.gov/pubmed/31829282
http://dx.doi.org/10.1186/s13148-019-0781-3