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Drug screening approach combines epigenetic sensitization with immunochemotherapy in cancer
BACKGROUND: The epigenome plays a key role in cancer heterogeneity and drug resistance. Hence, a number of epigenetic inhibitors have been developed and tested in cancers. The major focus of most studies so far has been on the cytotoxic effect of these compounds, and only few have investigated the a...
Autores principales: | Facciotto, Chiara, Casado, Julia, Turunen, Laura, Leivonen, Suvi-Katri, Tumiati, Manuela, Rantanen, Ville, Kauppi, Liisa, Lehtonen, Rainer, Leppä, Sirpa, Wennerberg, Krister, Hautaniemi, Sampsa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907220/ https://www.ncbi.nlm.nih.gov/pubmed/31829282 http://dx.doi.org/10.1186/s13148-019-0781-3 |
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