Effective machine-learning assembly for next-generation amplicon sequencing with very low coverage

BACKGROUND: In short-read DNA sequencing experiments, the read coverage is a key parameter to successfully assemble the reads and reconstruct the sequence of the input DNA. When coverage is very low, the original sequence reconstruction from the reads can be difficult because of the occurrence of un...

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Detalles Bibliográficos
Autores principales: Ranjard, Louis, Wong, Thomas K. F., Rodrigo, Allen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907241/
https://www.ncbi.nlm.nih.gov/pubmed/31829137
http://dx.doi.org/10.1186/s12859-019-3287-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907241/
https://www.ncbi.nlm.nih.gov/pubmed/31829137
http://dx.doi.org/10.1186/s12859-019-3287-2

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