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Effective machine-learning assembly for next-generation amplicon sequencing with very low coverage
BACKGROUND: In short-read DNA sequencing experiments, the read coverage is a key parameter to successfully assemble the reads and reconstruct the sequence of the input DNA. When coverage is very low, the original sequence reconstruction from the reads can be difficult because of the occurrence of un...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907241/ https://www.ncbi.nlm.nih.gov/pubmed/31829137 http://dx.doi.org/10.1186/s12859-019-3287-2 |