Targeted regulation of fibroblast state by CRISPR-mediated CEBPA expression

BACKGROUND: Fibroblasts regulate tissue homeostasis and the balance between tissue repair and fibrosis. CCAAT/enhancer-binding protein alpha (CEBPA) is a key transcription factor that regulates adipogenesis. CEBPA has been shown to be essential for lung maturation, and deficiency of CEBPA expression...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Meridew, Jeffrey A., Aravamudhan, Aja, Ligresti, Giovanni, Tschumperlin, Daniel J., Tan, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907247/
https://www.ncbi.nlm.nih.gov/pubmed/31829168
http://dx.doi.org/10.1186/s12931-019-1253-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907247/
https://www.ncbi.nlm.nih.gov/pubmed/31829168
http://dx.doi.org/10.1186/s12931-019-1253-1

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