The atypical cyclin-like protein Spy1 overrides p53-mediated tumour suppression and promotes susceptibility to breast tumourigenesis

BACKGROUND: Breast cancer is the most common cancer to affect women and one of the leading causes of cancer-related deaths. Proper regulation of cell cycle checkpoints plays a critical role in preventing the accumulation of deleterious mutations. Perturbations in the expression or activity of mediat...

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Detalles Bibliográficos
Autores principales: Fifield, Bre-Anne, Qemo, Ingrid, Kirou, Evie, Cardiff, Robert D., Porter, Lisa Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907270/
https://www.ncbi.nlm.nih.gov/pubmed/31829284
http://dx.doi.org/10.1186/s13058-019-1211-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907270/
https://www.ncbi.nlm.nih.gov/pubmed/31829284
http://dx.doi.org/10.1186/s13058-019-1211-3

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