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Time-resolved evaluation of compound repositioning predictions on a text-mined knowledge network

BACKGROUND: Computational compound repositioning has the potential for identifying new uses for existing drugs, and new algorithms and data source aggregation strategies provide ever-improving results via in silico metrics. However, even with these advances, the number of compounds successfully repo...

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Detalles Bibliográficos
Autores principales: Mayers, Michael, Li, Tong Shu, Queralt-Rosinach, Núria, Su, Andrew I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907279/
https://www.ncbi.nlm.nih.gov/pubmed/31829175
http://dx.doi.org/10.1186/s12859-019-3297-0