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LNA-anti-miR-150 ameliorated kidney injury of lupus nephritis by inhibiting renal fibrosis and macrophage infiltration

BACKGROUND: The prevalence of lupus nephritis (LN) remains high despite various emerging monoclonal antibodies against with targeting systemic lupus erythematosus (SLE). Renal fibrosis is the main feature of late stage LN, and novel therapeutic agents are still needed. We previously reported that mi...

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Detalles Bibliográficos
Autores principales: Luan, Junjun, Fu, Jingqi, Chen, Chengjie, Jiao, Congcong, Kong, Weiwei, Zhang, Yixiao, Chang, Qing, Wang, Yanqiu, Li, Detian, Illei, Gabor G., Kopp, Jeffrey B., Pi, Jingbo, Zhou, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907329/
https://www.ncbi.nlm.nih.gov/pubmed/31829247
http://dx.doi.org/10.1186/s13075-019-2044-2